Hedgehog signaling

Potent, selective, irreversible proteasome inhibitor

Na²⁺ / K⁺ / Ca²⁺ channel inhibitor. Anticonvulsant.

Acyl-CoA cholesterol acyltransferase (ACAT) inhibitor

Actin polymerization inhibitor

Potent EGFR tyrosine kinase inhibitor

Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.

Antibiotic. Inhibits nuclear export of protiens.

Potent, non-selective tyrosine kinase inhibitor

Reversible trypsin-like and cysteine proteases inhibitor

Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.