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Jedi2

(HB8049)
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Product overview

Name Jedi2
Purity >98%
Description Piezo1 channel activator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description

Piezo1 channel activator which promotes calcium influx into HEK293 cells expressing Piezo1. Shows various effects such as causing a loss of typical red blood cell shape causes RBC dehydration.

Solubility & Handling

Solubility overview Soluble in DMSO (100 mM), and in ethanol (100 mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
Molecular Weight 208.23
Chemical structure Jedi2 [651005-90-2] Chemical Structure
Molecular Formula C10H8O3S
CAS Number 651005-90-2
PubChem identifier 2796026
SMILES CC1=C(C=C(O1)C2=CC=CS2)C(=O)O
InChi InChI=1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
InChiKey YXDCRSXNEOKXDE-UHFFFAOYSA-N
MDL number MFCD01569561

References for Jedi2

References are publications that support the biological activity of the product

  • Impact of PIEZO1-channel on inflammation and osteoclastogenesis mediated via periodontal ligament fibroblasts during mechanical loading.

    Schröder A et al (2023) European journal of oral sciences 131 : e12913
    Read more (PubMedID: 36635063)

  • Impact of PIEZO1-channel on inflammation and osteoclastogenesis mediated via periodontal ligament fibroblasts during mechanical loading.

    Schröder A et al (2023) European journal of oral sciences 131 : e12913
    Read more (PubMedID: 36635063)

  • A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel.

    Wang Y et al (2018) Nature communications 9 : 1300
    Read more (PubMedID: 29610524)

3 Item(s)

Related Products
Grouped product items
Order: HB8049
Pack PriceQty
10mg
$112
50mg
$464
Piezo1 channel activator
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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