Jasplakinolide

(HB3946)
Technical documents: SDS CoA Datasheet
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Product overview

Name Jasplakinolide
Purity >98%
Description Cell permeable, non-fluorescent F-actin probe. Induces actin polymerization and stabilization.
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Biological Data

Biological description Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for autophagy/phagocytosis research.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
Molecular Weight 709.7
Chemical structure Jasplakinolide [102396-24-7] Chemical Structure
Molecular Formula C36H45BrN4O6
CAS Number 102396-24-7
PubChem identifier 9831636
SMILES C[C@H](C[C@H](C)OC1=O)/C=C(C)/C[C@H](C)C(N[C@H](C(N([C@H](CC2=C(Br)NC3=C2C=CC=C3)C(N[C@@H]([C@]4=CC=C(O)C=C4)C1)=O)C)=O)C)=O
InChiKey GQWYWHOHRVVHAP-DHKPLNAMSA-N
Appearance Off-white solid