Reprogramming
Repogramming is the process of reverting mature, specialized cells into pluripotent stem cells. iPSCs are generated by artificial expression of key transcription factors under specific culture conditions. Researchers can save up to 50% on small molecules which modulate stem cell reprogramming from Hello Bio - they are up to half the price of other suppliers.
Minocycline hydrochloride (HB4617)
Description:Broad spectrum antibiotic. Potent microglial activation inhibitor. Allows formation of EPSs.
Purity:>98%
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PD 0325901 (HB2240)
Description:Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.
Purity:>98%
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Pifithrin-μ (HB3025)
Description:p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.
Purity:>99%
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RepSox (HB3301)
Description:Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.
Purity:>99%
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RG 108 (HB1377)
Description:Non-nucleoside DNA methyltransferase inhibitor. Enhances iPSC generation efficiency.
Purity:>99%
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SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
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Thiazovivin (HB3240)
Description:Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.
Purity:>97%
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Tranylcypromine hydrochloride (HB1412)
Description:LSD1 / MAO inhibitor. Enables reprogramming of mouse embryonic fibroblasts into iPS cells.
Purity:>98%
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Trichostatin A (HB1402)
Description:Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.
Purity:>98%
