Proliferation, self-renewal, maintenance
Stem cells have the ability to replicate continually. Proliferation is when a cell multiplies but does not change its cell type. Self renewal is the process of a stem cell dividing to produce at least one copy of itself. Small molecules such as SB 203580 and PGE2 stimulate proliferation. Researchers can save up to 50% on small molecules which modulate stem cell proliferation, self-renewal and maintenance from Hello Bio - they are up to half the price of other suppliers.Â
IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
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LY 294002 hydrochloride (HB2266)
Description:PI3-K inhibitor. Suppresses mESC proliferation.
Purity:>99%
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PD 102807 (HB1509)
Description:Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.
Purity:>98%
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PD 173074 (HB3584)
Description:FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.
Purity:>98%
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PD 98059 (HB2244)
Description:Selective MEK1/MAP2K inhibitor. Enhances ESC self-renewal.
Purity:>98%
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Pioglitazone hydrochloride (HB2554)
Description:Selective PPARγ agonist. Enhances mESCs proliferation and survival.
Purity:>99%
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Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
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Prostaglandin E2 (HB3460)
Description:Endogenous prostanoid. Induces hematopoietic stem cell proliferation. 3D growth matrix component and used in production of liver and prostate organoids.
Purity:>98%
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SB 202190 (HB1301)
Description:Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.
Purity:>99%
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SB 203580 (HB1302)
Description:Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.
Purity:>98%
