TLR7

mGlu₅ negative allosteric modulator

mGlu₄ positive allosteric modulator

Potent mGlu₄ positive allosteric modulator

mGlu₄ positive allosteric modulator

Potent mGlu₅ positive allosteric modulator

Potent, selective ATP-competitive p38 MAPK inhibitor

Potent, selective p38α MAPK inhibitor

Calmodulin (CaM) antagonist

Potent 5-HT_1A receptor antagonist. D₄ receptor agonist.

Selective IKKα and IKKβ kinase activity inhibitor. NF-κB inhibitor.