Vigabatrin

Name: Vigabatrin
Brand: Hello Bio
SKU: HB0868
Price: 77 USD
Availability: InStock

(HB0868)

Be the first to add a publication

Technical documents: SDS Datasheet

Product overview

Name

Vigabatrin

Alternative names

(±)-γ-Vinyl GABA

Purity

>98%

Description

Selective, irreversible GABA-T (transaminase) inhibitor

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3) Frequently bought together

Write Your Own Review

Images

Vigabatrin product vial image | Hello Bio

Biological Data

Biological description

Selective and irreversible GABA-T (transaminase) inhibitor. Inhibits GABA catabolism. Increases GABA levels in the brain and CSF while decreasing glutamate in a dose-dependent manner. Shows anticonvulsant and antidepressant actions.

Solubility & Handling

Storage instructions

+4°C (desiccate)

Solubility overview

Soluble in water (100mM)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>98%

Chemical name

4-Aminohexenoic acid

Molecular Weight

129.16

Chemical structure

Molecular Formula

C₆H₁₁NO₂

CAS Number

68506-86-5

PubChem identifier

5665

SMILES

NC(C=C)CCC(O)=O

InChiKey

PJDFLNIOAUIZSL-UHFFFAOYSA-N

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for Vigabatrin

References are publications that support the biological activity of the product

Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity.
Russo E et al (2011) Behav Brain Res 225(1) : 373-6.
Read more (PubMedID: 21807031)
Effects of vigabatrin (gamma-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats.
Halonen T et al (1991) Epilepsia 32(2) : 242-9.
Read more (PubMedID: 1672276)
Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes.
Larsson OM et al (1986) Neuropharmacology 25(6) : 617-25.
Read more (PubMedID: 3092125)

Selective, irreversible GABA-T (transaminase) inhibitor

New Products in this Area

Pexidartinib (PLX3397)

HB8991

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.

Order: HB0868
Pack	Price	Qty
10mg	$77
50mg	$325

Vigabatrin

Product overview

Images

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for Vigabatrin

Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity.

Effects of vigabatrin (gamma-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats.

Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes.

About you

Tell us about your publication!

Captcha

New Products in this Area

Vigabatrin

Product overview

Images

Vigabatrin product vial image | Hello Bio

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for Vigabatrin

Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity.

Effects of vigabatrin (gamma-vinyl GABA) on neurotransmission-related amino acids and on GABA and benzodiazepine receptor binding in rats.

Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes.

About you

Tell us about your publication!

Captcha

About you

How can we help you?

New Products in this Area

Related Products