TLR (Toll-like receptors)
Toll-like receptors (TLRs) are found on various immune cells and are essential in the innate immune response. TLRS signal through the recruitment of specific adaptor molecules which leads to NF-kB and IRF activation. Researchers can save up to 50% on TLR ligands from Hello Bio - they are around half the price of other suppliers.
Ionomycin free acid (HB1002)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
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IPTG (HB3941)
Description:Protein expression inducer. Frequently used with X-Gal in cloning procedures.
Purity:>99%
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Ivermectin (IVM) (HB1958)
Description:α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.
Purity:>95%
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IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
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IWP 4 (HB3066)
Description:Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.
Purity:>98%
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JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
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LDN193189 hydrochloride (LDN) (HB5624)
Description:Potent, selective ALK2/ALK3 inhibitor which also promotes neural induction of hPSCs. May be used as a component for brain organoid production.
Purity:>98%
