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JAK/STAT
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JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
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LY 294002 hydrochloride (HB2266)
Description:PI3-K inhibitor. Suppresses mESC proliferation.
Purity:>99%
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MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
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Monensin sodium salt (HB4882)
Description:Protein transport inhibitor. Commonly used in cytokine staining.
Purity:>98%
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Niclosamide (HB1435)
Description:STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.
Purity:>98%
