JAK/STAT

JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
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  1. 1  Review
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    Description:

    Calcium sensing receptor (CaSR) agonist. Induces MSC osteogenic differentiation.

    Pack:
    1g
    Price:
    $106
    Qty:
  2. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $144
    Qty:
  3. Description:

    Thyroid hormone. Frequently used in various stem cell protocols.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    Qty:
    Pack:
    100mg
    Price:
    $59
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    Pack:
    250mg
    Price:
    $145
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  4. Description:

    Serotonin/norepinephrine re-uptake inhibitor. Affects differentiation of NSCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $76
    Qty:
    Pack:
    50mg
    Price:
    $287
    Qty:
  5. WHI-P 154 (HB1431)

    Description:

    Non-selective JAK3 inhibitor and potent EGFR inhibitor. Induces neural progenitor cell differentiation.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $85
    Qty:
    Pack:
    25mg
    Price:
    $307
    Qty:
  6. Wnt-C59 (HB3155)

    Description:

    Highly potent PORCN inhibitor. Induces iPSC cardiomyocytes differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $271
    Qty:
    Pack:
    50mg
    Price:
    $1,056
    Qty:
  7. XAV 939 (HB0660)

    Description:

    Potent tankyrase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $115
    Qty:
    Pack:
    25mg
    Price:
    $257
    Qty:
    Pack:
    50mg
    Price:
    $465
    Qty:
  8. 9  Reviews
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $46
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $124
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    5x10mg
    Price:
    $786
    Qty:
    Pack:
    25mg
    Price:
    $339
    Qty:
    Pack:
    50mg
    Price:
    $588
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $180
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $426
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $710
    Qty:
  9. Zebularine (HB1378)

    Description:

    DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $43
    Qty:
    Pack:
    5mg
    Price:
    $92
    Qty:
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