Inflammasome
Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
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PluriSln 1 (HB3573)
Description:SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.
Purity:>99%
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Pexidartinib (PLX3397) (HB8991)
Description:Potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
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PLX4720 (HB4030)
Description:Potent and selective cell permeable B-Raf and C-Raf inhibitor
Purity:>99%
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PLX5622 (HB17582)
Description:Highly selective, potent CSF-1R inhibitor. Widely used microglia-depletion agent.
Purity:>98%
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PNU 37883 hydrochloride (HB1105)
Description:Selective vascular KATP channel antagonist
Purity:>99%
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PNU 74654 (HB0528)
Description:β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.
Purity:>99%
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