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Biological Data
| Biological description | Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. |
Solubility & Handling
| Storage instructions | +4°C |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide |
| Chemical structure | ![PLX4720 [918505-84-7] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "PLX4720 [918505-84-7]") |
| InChiKey | YZDJQTHVDDOVHR-UHFFFAOYSA-N |
| Appearance | Off-white solid |
Potent and selective cell permeable B-Raf and C-Raf inhibitor
![PLX4720 [918505-84-7] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb4030.png "PLX4720 [918505-84-7]")
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