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PKA Inhibitor IV

(HB0509)
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Product overview

Name PKA Inhibitor IV
Alternative names PKI (5-24)
Description Potent, selective PKA inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (2)
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Biological Data

Biological description Potent and selective protein kinase A (PKA) inhibitor (Ki = 2.8 nM).

Solubility & Handling

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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x
More Info

Dilution

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x
More Info

Chemical Data

Chemical name L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-a-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-larginyl-L-aspartic acid
Molecular Weight 2222.4
Molecular Formula C18H24N4O3S.2HCl
CAS Number 99534-03-9
SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)O)C(C)O)[C@@H](C)CC)C(C)O)C(=O)N[C@@H](Cc3[nH]cnc3)C(=O)N[C@@H](CC(O)=O)C(O)=O

References for PKA Inhibitor IV

References are publications that support the biological activity of the product

  • Sargaquinoic acid promotes neurite outgrowth via protein kinase A and MAP kinases-mediated signaling pathways in PC12D cells.

    Kamei Y et al (2003) Int J Dev Neurosci 21(5) : 255-62.
    Read more (PubMedID: 12850058)

  • Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat.

    Boylan JM et al (2001) J Biol Chem 276(48) : 44457-63.
    Read more (PubMedID: 11574531)

2 Item(s)

Grouped product items
Order: HB0509
Pack PriceQty
500μg
$410
Potent, selective PKA inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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