Selective vascular KATP channel antagonist (IC50 values are 15 and 6 µM for SUR2B/ Kir6.2 and SUR2B/ Kir6.1 channels respectively). Also Kir6.2δ26 channel inhibitor (IC50 = 5.0 µM). Displays no activity at cardiac, pancreatic or skeletal kATP channels. Displays diuretic properties.
Solubility & Handling
Solubility overview
Soluble in DMSO (25mM) or ethanol (100mM)
Storage instructions
room temperature (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.