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Inflammasome
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Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
IEM-1460 (HB0338)
Description:Competitive, selective, GluA2 (GluR2)-lacking AMPA receptor blocker
Purity:>98%
Ifenprodil (HB0339)
Description:Non-competitive GluN2B subunit selective NMDAR allosteric inhibitor
Purity:>99%
Imatinib mesylate (HB1943)
Description:Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases
Purity:>98%