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Biological Data Biological description Endogenous histamine receptor agonist. Shows vasodilatory, bronchoconstrictory, immunomodulatory, anti-tumor and cytoprotective actions.
Solubility & Handling Solubility overview Soluble in water (100 mM) and in DMSO (100 mM)
Storage instructions Room temperature (desiccate)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 2-(1H-imidazol-5-yl)ethanamine dihydrochloride
Chemical structure
Molecular Formula C5 H9 N3 .2HCl
SMILES C1=C(NC=N1)CCN.Cl.Cl
InChi InChI=1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
InChiKey PPZMYIBUHIPZOS-UHFFFAOYSA-N
References for Histamine dihydrochloride References are publications that support the biological activity of the product
Histamine and its receptors. Parsons ME et al (2006) Br J Pharmacol 147 Suppl 1 : S127-35. Histamine dihydrochloride protects against early alcohol-induced liver injury in a rat model. Hornyak SC et al (2003) Inflammation 27(5) : 317-27. Monotherapy with histamine dihydrochloride suppresses in vivo growth of a rat sarcoma in liver and subcutis. Rizell M et al (2002) Anticancer Res 22(4) : 1943-8.
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Endogenous histamine receptor agonist