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Biological Data
| Biological description | Endogenous histamine receptor agonist. Shows vasodilatory, bronchoconstrictory, immunomodulatory, anti-tumor and cytoprotective actions. |
Solubility & Handling
| Storage instructions | Room temperature (desiccate) |
| Solubility overview | Soluble in water (100 mM) and in DMSO (100 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 2-(1H-imidazol-5-yl)ethanamine dihydrochloride |
| Chemical structure | ![Histamine dihydrochloride [56-92-8] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Histamine dihydrochloride [56-92-8]") |
| Molecular Formula | C5H9N3.2HCl |
| SMILES | C1=C(NC=N1)CCN.Cl.Cl |
| InChi | InChI=1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H |
| InChiKey | PPZMYIBUHIPZOS-UHFFFAOYSA-N |
References for Histamine dihydrochloride
References are publications that support the biological activity of the product
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Histamine and its receptors.
Parsons ME et al (2006) Br J Pharmacol 147 Suppl 1 : S127-35. -
Histamine dihydrochloride protects against early alcohol-induced liver injury in a rat model.
Hornyak SC et al (2003) Inflammation 27(5) : 317-27. -
Monotherapy with histamine dihydrochloride suppresses in vivo growth of a rat sarcoma in liver and subcutis.
Rizell M et al (2002) Anticancer Res 22(4) : 1943-8.
Endogenous histamine receptor agonist
![Histamine dihydrochloride [56-92-8] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb2803.png "Histamine dihydrochloride [56-92-8]")
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