Product overview

Name Histatin 5
Biological description

Salivary peptide with broad spectrum antimicrobial action including against gram positive and gram negative bacteria. Induces the formation of ROS (reactive oxygen species) to disrupt mitochondrial respiration. Shows antifungal activity.

Alternative names Hst-5
Purity >95%
Description

Antimicrobial salivary peptide

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Solubility & Handling

Storage instructions -20°C
Solubility overview

Soluble in acidic buffer

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 3036.3
Molecular Formula C133H195N51O33
Sequence (one letter) DSHAKRHHGYKRKFHEKHHSHRGY
Sequence (three letter) H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH

References for Histatin 5

References are publications that support the biological activity of the product
  • Histatin 5 Metallopeptides and Their Potential against <i>Candida albicans</i> Pathogenicity and Drug Resistance

    Zolin GVS et al (2021) Biomolecules 11(8) : 0
  • The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive oxygen species

    Helmerhorst EJ et al (2001) Proc Natl Acad Sci U S A 98(25) : 14637-42
  • Effects of histatin 5 and derived peptides on Candida albicans

    Ruissen AL et al (2001) Biochem J 356(Pt 2) : 361-8

3 Item(s)