Phosphoinositide 3-kinase (PI3K)/Akt pathway inhibitor. Inhibits NO, prostaglandin E2 and TNF-α production. Inhibits NFκB and scavenges superoxide and peroxyl radicals. Shows anti-inflammatory, antitumor and anti-angiogenic actions.
Solubility & Handling
Solubility overview
Soluble in DMSO (100 mM) and in ethanol (100 mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells.
Yang SE et al (2002) Biochem Pharmacol 63(9) : 1641-51.
![Honokiol [35354-74-6] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0328.png "Honokiol [35354-74-6]")
Understanding purity and quality - a guide for life scientists