Inflammasome
Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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Carboplatin (HB3824)
Description:Cisplatin analog. Blocks DNA replication and transcription.
Purity:>98%
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(S)-4-Carboxyphenylglycine (HB0049)
Description:Competitive, selective group 1 mGlu antagonist
Purity:>99%
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CAT335 (HB8146)
Description:K2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1CG* but not wild-type K2P2.1 (TREK-1)
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Purity:>98%
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CCG 1423 (HB3389)
Description:Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.
Purity:>99%
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Ceftriaxone disodium salt (HB0176)
Description:β-lactam antibiotic. Increases EAAT2 activity.
Purity:>98%
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Celastrol (HB4605)
Description:Anti-oxidant, anti-inflammatory compound with many actions. Topoisomerase II inhibitor.
Purity:>98%
