Carboxy-PTIO, potassium salt

Technical documents: SDS Datasheet

Product overview

Name Carboxy-PTIO, potassium salt
Purity >98%
Description NO scavenger
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Biological Data

Biological description Nitric oxide (NO) scavenging free radical. Reacts with NO stoichiometrically. Reduces withdrawal-induced anxiety behaviours.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in water (100mg/ml) or DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



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Chemical Data

Purity >98%
Chemical name 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potassium salt
Molecular Weight 315.39
Chemical structure Carboxy-PTIO, potassium salt  [148819-94-7] Chemical Structure
Molecular Formula C14H16KN2O4
CAS Number 148819-94-7
PubChem identifier 2733502
SMILES CC1(C([N+](=C(N1[O])C2=CC=C(C=C2)C(=O)[O-])[O-])(C)C)C.[K+]

References for Carboxy-PTIO, potassium salt

References are publications that support the biological activity of the product
  • Effects of nitric oxide synthase inhibition in the dorsolateral periaqueductal gray matter on ethanol withdrawal-induced anxiety-like behavior in rats.

    Bonassoli VT et al (2013) Psychopharmacology (Berl) 228(3) : 487-98.
  • Nitric oxide scavenging causes remodeling of the endoplasmic reticulum, Golgi apparatus and mitochondria in pulmonary arterial endothelial cells.

    Lee JE et al (2013) Nitric Oxide 33 : 64-73.
  • Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies.

    Tsunoda R et al (1994) Eur J Pharmacol 262(1-2) : 55-63.
  • Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction.

    Akaike T et al (1993) Biochemistry 32(3) : 827-32.

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