Carboxy-PTIO, potassium salt

(HB0169)

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Product overview

Name Carboxy-PTIO, potassium salt
Purity >98%
Description NO scavenger
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Biological Data

Biological description Nitric oxide (NO) scavenging free radical. Reacts with NO stoichiometrically. Reduces withdrawal-induced anxiety behaviours.

Solubility & Handling

Solubility overview Soluble in water (100mg/ml) or DMSO
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potassium salt
Molecular Weight 315.39
Chemical structure Carboxy-PTIO, potassium salt  [148819-94-7] Chemical Structure
Molecular Formula C14H16KN2O4
CAS Number 148819-94-7
PubChem identifier 2733502
SMILES CC1(C([N+](=C(N1[O])C2=CC=C(C=C2)C(=O)[O-])[O-])(C)C)C.[K+]
InChiKey VYEUQMVIGXFZQU-UHFFFAOYSA-M

References for Carboxy-PTIO, potassium salt

References are publications that support the biological activity of the product
  • Effects of nitric oxide synthase inhibition in the dorsolateral periaqueductal gray matter on ethanol withdrawal-induced anxiety-like behavior in rats.

    Bonassoli VT et al (2013) Psychopharmacology (Berl) 228(3) : 487-98.
  • Nitric oxide scavenging causes remodeling of the endoplasmic reticulum, Golgi apparatus and mitochondria in pulmonary arterial endothelial cells.

    Lee JE et al (2013) Nitric Oxide 33 : 64-73.
  • Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies.

    Tsunoda R et al (1994) Eur J Pharmacol 262(1-2) : 55-63.
  • Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction.

    Akaike T et al (1993) Biochemistry 32(3) : 827-32.

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