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Biological Data Biological description Nitric oxide (NO) scavenging free radical. Reacts with NO stoichiometrically. Reduces withdrawal-induced anxiety behaviours.
Solubility & Handling Storage instructions +4°C
Solubility overview Soluble in water (100mg/ml) or DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potassium salt
Chemical structure
Molecular Formula C14 H16 KN2 O4
PubChem identifier 2733502
SMILES CC1(C([N+](=C(N1[O])C2=CC=C(C=C2)C(=O)[O-])[O-])(C)C)C.[K+]
InChiKey VYEUQMVIGXFZQU-UHFFFAOYSA-M
References for Carboxy-PTIO, potassium salt References are publications that support the biological activity of the product
Effects of nitric oxide synthase inhibition in the dorsolateral periaqueductal gray matter on ethanol withdrawal-induced anxiety-like behavior in rats. Bonassoli VT et al (2013) Psychopharmacology (Berl) 228(3) : 487-98. Nitric oxide scavenging causes remodeling of the endoplasmic reticulum, Golgi apparatus and mitochondria in pulmonary arterial endothelial cells. Lee JE et al (2013) Nitric Oxide 33 : 64-73. Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies. Tsunoda R et al (1994) Eur J Pharmacol 262(1-2) : 55-63. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction. Akaike T et al (1993) Biochemistry 32(3) : 827-32.
![Carboxy-PTIO, potassium salt [148819-94-7] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0169.png "Carboxy-PTIO, potassium salt [148819-94-7]")
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