Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
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SNX 482 (HB1235)
Description:Reported to be a potent, selective Cav2.3 (R-type) channel blocker
Purity:>95%
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Sodium butyrate (HB1399)
Description:HDAC inhibitor. Directs mESC differentiation into hepatocytes.
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SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%
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Spadin (HB5438)
Description:Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.
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Spiperone hydrochloride (HB1656)
Description:Selective D2-like receptor antagonist. 5-HT2A antagonist.
Purity:>98%
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Spironolactone (HB2799)
Description:Mineralocorticoid and androgen receptor antagonist
Purity:>98%
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Splitomicin (HB4091)
Description:Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor
Purity:>98%
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