Cytokine Storm / Immune response signaling

Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

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  1. Description:

    Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker. 1mM solution (in 1mL DMSO)

    Pack:
    1mL
    Price:
    $274
    Qty:
  2. PAC 1 (HB1291)

    Description:

    Procaspase-activating compound

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $578
    Qty:
  3. Palitantin (HB4012)

    Description:

    Metabolite of Penicillium with antiprotozoal and antifungal activity

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $227
    Qty:
  4. Description:

    Spirobisnaphthalene derivative

    Purity:

    >96%

    Pack:
    5mg
    Price:
    $441
    Qty:
  5. Pam2CSK4 (HB3086)

    Description:

    TLR2/6 activator. Induces potent NF-κB activation and cytokine production.

    Pack:
    1mg
    Price:
    $157
    Qty:
  6. Pam3CSK4 (HB3428)

    Description:

    TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

    Pack:
    1mg
    Price:
    $147
    Qty:
  7. Description:

    100 tablets of PBS

    Pack:
    Pack
    Price:
    $91
    Qty:
  8. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $28
    Qty:
    Pack:
    5×2mg
    Price:
    $115
    Qty:
    Pack:
    10mg
    Price:
    $109
    Qty:
    Pack:
    50mg
    Price:
    $308
    Qty:
  9. PD 102807 (HB1509)

    Description:

    Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $287
    Qty:
  10. PD 173074 (HB3584)

    Description:

    FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $835
    Qty:
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