Pharmacological disease models
Small molecules and excitotoxic agents can be used to pharmacologically induce disease models such as epilepsy, Parkinson's Disease, catalepsy, Schizophrenia, pain and diabetes models. Researchers can save up to 50% on excitotoxic agents - they are up to half the price of other suppliers.
(R)-3-Hydroxybutyric acid (HB4640)
Description:Endogenous HDAC1, HDAC3 and HDAC4 inhibitor
Purity:>98%
(S)-3-Hydroxybutyric acid (HB4641)
Description:Endogenous HDAC1, HDAC3 and HDAC4 inhibitor
Purity:>98%
- Description:
Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%
(R,R)-Hymeglusin (HB3701)
Description:Specific and irreversible HMG-CoA synthase inhibitor
Purity:>95%
10Z-Hymenialdisine (HB1264)
Description:Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.
Purity:>97%
I-BET 151 hydrochloride (HB1446)
Description:BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes
Purity:>98%