Fluorescent ligands
Fluorescent ligands are suitable for a wide range of applications which include localizing receptor distribution in tissues and cells, and live-cell imaging of receptor kinetics. Ligands such as CellAuara fluorescent ligands target G protein coupled receptors (GPCRs) and are comprised of three units:a pharmacophore (agonist or antagonist), a fluorescent dye (the fluorophore) and a linker - which connects the pharmacophore with the dye. Researchers can save up to 50% on fluorescent ligands from Hello Bio - they are up to half the price of other suppliers.
View resources: Introducing CellAura Fluorescent GPCR ligands
Ivermectin (IVM) (HB1958)
Description:α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.
Purity:>95%
IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
IWP 4 (HB3066)
Description:Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.
Purity:>98%
Jasplakinolide (HB3946)
Description:Cell permeable, non-fluorescent F-actin probe. Induces actin polymerization and stabilization.
Purity:>98%
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
JF-NP-26 (Caged-Raseglurant) (HB6127)
Description:Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.
Purity:>98%