Chemogenetics
Chemogenetics research involves the use of small molecule ligands that selectively target genetically-modified receptors (Designer Receptors Exclusively Activated by Designer Drugs or DREADDs) or chimeric ion channels (Pharmacologically Selective Actuator Modules or PSAMs) to modulate and control neuronal activity. Researchers can save up to 50% on chemogenetics research products from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View products: DREADDs | PSEMS | CATKLAMP View Resources: DREADDs Mini-Review | DREADDs for studying GPCRs
- Description:
Fluorescent M3 muscarinic receptor antagonist
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N-Desmethylclozapine (HB2136)
Description:Biologically active metabolite of clozapine.
Purity:>99%
- Description:
Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.
Purity:>98%
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DREADD agonist 21 (Compound 21) (HB4888)
Description:Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.
Purity:>98%
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Iperoxo (HB9785)
Description:Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniGq receptor.
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PD 102807 (HB1509)
Description:Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.
Purity:>98%
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VU 0357017 hydrochloride (HB1498)
Description:Potent, selective M1 receptor allosteric agonist
Purity:>98%
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