Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
MG132 (HB4135)
Description:Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.
Purity:>95%
MK-2206 dihydrochloride (HB5934)
Description:Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.
Purity:>98%
Oxazole Yellow Iodide (HB6210)
Description:Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker.
- Description:
Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker. 1mM solution (in 1mL DMSO)