Inhibits proliferation of various cell types. Inhibits DNA synthesis by forming covalent crosslinks between complementary DNA strands.
Widely used for treatment of feeder cell layers (e.g. for PMEF (primary mouse embryonic fibroblasts) and CD1 mouse embryonic fibroblasts (MEFs) and hESCs (human embryonic stem cells).
Also shows antitumor activity.
Solubility & Handling
Solubility overview
Soluble in DMSO (100 mM) and water (5 mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists