Product overview

Name PETCM
Purity >99%
Description Caspase-3 activator
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Biological Data

Biological description Caspase-3 activator. Inhibits ProT and stimulates apoptosome formation. Promotes Apaf-1 oligomerization. Shows apoptotic actions.

Solubility & Handling

Solubility overview Soluble in HCl (50mM, 1eq. HCl)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name α-(Trichloromethyl)-4-pyridineethanol
Molecular Weight 240.52
Molecular Formula C8H8Cl3NO
CAS Number 10129-56-3
PubChem identifier 224859
SMILES OC(CC1=CC=NC=C1)C(Cl)(Cl)Cl
InChiKey NGTDJJKTGRNNAU-UHFFFAOYSA-N

References for PETCM

References are publications that support the biological activity of the product
  • Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.

    Jiang X et al (2003) Science 299(5604) : 223-6.
  • Direct activation of the apoptosis machinery as a mechanism to target cancer cells.

    Nguyen JT et al (2003) Proc Natl Acad Sci U S A 100(13) : 7533-8.

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