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Biological Data

Biological description Caspase-3 activator. Inhibits ProT and stimulates apoptosome formation. Promotes Apaf-1 oligomerization. Shows apoptotic actions.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in HCl (50mM, 1eq. HCl)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Chemical name α-(Trichloromethyl)-4-pyridineethanol
Molecular Weight 240.52
Molecular Formula C8H8Cl3NO
CAS Number 10129-56-3
PubChem identifier 224859
SMILES OC(CC1=CC=NC=C1)C(Cl)(Cl)Cl
InChiKey NGTDJJKTGRNNAU-UHFFFAOYSA-N

References for PETCM

References are publications that support the biological activity of the product
  • Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.

    Jiang X et al (2003) Science 299(5604) : 223-6.
  • Direct activation of the apoptosis machinery as a mechanism to target cancer cells.

    Nguyen JT et al (2003) Proc Natl Acad Sci U S A 100(13) : 7533-8.