Glutamate uptake & transport
Glutamate transport is mediated by a family of transmembrane proteins known as glutamate transporters, or excitatory amino acid transporters (EAATs). EAATs are sodium- and potassium-dependent members of the Solute Carrier Family 1 (SLC1). The five EAAT subtypes are EAAT1 (Excitatory amino acid transporter 1 / SLC1A3) , EAAT2 (Excitatory amino acid transporter 2 / SLC1A2), EAAT3 (Excitatory amino acid transporter 3 / SLC1A1), EAAT4 (Excitatory amino acid transporter 4 / SLC1A6) and EAAT5 (Excitatory amino acid transporter 5 / SLC1A7). Researchers can save up to 50% on EAAT inhibitors, activators and modulators from Hello Bio - they are up to half the price of other suppliers.
IEM-1460 (HB0338)
Description:Competitive, selective, GluA2 (GluR2)-lacking AMPA receptor blocker
Purity:>98%
Ifenprodil (HB0339)
Description:Non-competitive GluN2B subunit selective NMDAR allosteric inhibitor
Purity:>99%
Imatinib mesylate (HB1943)
Description:Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases
Purity:>98%