(-)-Indolactam V

Name: (-)-Indolactam V
SKU: HB0002
Price: 257 USD
Availability: InStock

(HB0002)

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Technical documents: Datasheet

Product overview

Name

(-)-Indolactam V

Purity

>99%

Description

Synthetic PKC activator

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (4)

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Biological Data

Biological description

Synthetic protein kinase C (PKC) inhibitor. Also induces embryonic stem cell differentiation. Displays tumor promoting properties with mitogenic and comitogenic activating effects.

Solubility & Handling

Storage instructions

-20°C (desiccate)

Solubility overview

Soluble in DMSO (10mM)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>99%

Chemical name

(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one

Molecular Weight

301.38

Chemical structure

Molecular Formula

C₁₇H₂₃N₃O₂

CAS Number

90365-57-4

SMILES

CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for (-)-Indolactam V

References are publications that support the biological activity of the product

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.
Chen S et al (2009) Nat Chem Biol 5(4) : 258-65.
Read more (PubMedID: 19287398)
Synthesis and biological activities of indolactone-V, the lactone analogue of the tumor promoter (-)-indolactam-V.
Nakagawa Y et al (1997) Biosci Biotechnol Biochem 61(8) : 1415-7.
Read more (PubMedID: 9301127)
(-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways.
Papadogiannakis N (1995) Cell Immunol 162(2) : 288-94.
Read more (PubMedID: 7743557)
(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.
Heikkilä J et al (1989) Biochem Biophys Res Commun 162(3) : 1207-13.
Read more (PubMedID: 2764930)

Synthetic PKC activator

Order: HB0002
Pack	Price	Qty
1mg	$257

(-)-Indolactam V

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for (-)-Indolactam V

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

Synthesis and biological activities of indolactone-V, the lactone analogue of the tumor promoter (-)-indolactam-V.

(-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways.

(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.

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(-)-Indolactam V

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for (-)-Indolactam V

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

Synthesis and biological activities of indolactone-V, the lactone analogue of the tumor promoter (-)-indolactam-V.

(-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways.

(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.

About you

Tell us about your publication!

Captcha

About you

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New Products in this Area