Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 531-540 of 1212

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  1. Description:

    Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

    Purity:

    >97%

    Pack:
    250μg
    Price:
    $201
    Qty:
    Pack:
    1mg
    Price:
    $669
    Qty:
  2. Description:

    Selective TRPC6 channel activator and neurotransmitter re-uptake inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $261
    Qty:
  3. Hypericin (HB3934)

    Description:

    Photosensitive compound. Shows anticancer, antiviral and antidepressant action.

    Pack:
    5mg
    Price:
    $300
    Qty:
  4. Hypotaurine (HB2656)

    Description:

    Non-selective endogenous glycine receptor agonist 

    Purity:

    >95%

    Pack:
    100mg
    Price:
    $101
    Qty:
  5. Pack:
    100μg
    Price:
    $243
    Qty:
  6. Description:

    BET bromodomain inhibitor, also promotes differentiation of hiPSCs into megakaryocytes

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $1,242
    Qty:
  7. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    Qty:
    Pack:
    500mg
    Price:
    $134
    Qty:
  8. Pack:
    1mg
    Price:
    $86
    Qty:
    Pack:
    5mg
    Price:
    $274
    Qty:
    Pack:
    25mg
    Price:
    $876
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $36
    Qty:
  9. Ibrutinib (HB4204)

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    Description:

    Potent, selective Bruton's tyrosine kinase (BTK) inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $151
    Qty:
    Pack:
    25mg
    Price:
    $455
    Qty:
  10. Pack:
    10mg
    Price:
    $176
    Qty:
    Pack:
    50mg
    Price:
    $705
    Qty:
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