Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
Yoda2 (KC289) (HB9134)
Description:Novel, selective Piezo1 channel activator. Improved efficacy, potency and solubility compared to Yoda1.
Zacopride hydrochloride (HB1694)
Description:Potent 5-HT3 antagonist and 5-HT4 agonist. Also selective IK1 channel agonist.
Purity:>99%
Zatebradine hydrochloride (HB1151)
Description:HCN channel blocker. Potent, selective bradycardic agent.
Purity:>95%
ZD 7288 (HB1152)
Description:HCN channel blocker. Modulates sino-atrial node function.
Purity:>98%
Zebularine (HB1378)
Description:DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.
Purity:>99%