Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Compound E (HB3849)
Description:Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.
Purity:>98%
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ω-Conotoxin GVIA (HB1218)
Description:Potent, selective Cav2.2 (N-type) channel blocker
Purity:>98%
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ω-Conotoxin MVIIC (HB1219)
Description:N-, P- and Q-type voltage-dependent Ca2+ channel blocker
Purity:>99%
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CP 465022 hydrochloride (HB0214)
Description:Potent, non-competitive AMPA receptor antagonist
Purity:>99%
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