Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
CGP 37157 (HB1132)
Description:Potent, selective mitochondria Na+ / Ca2+ exchange inhibitor
Purity:>99%
CGP 54626 hydrochloride (HB0959)
Description:Potent, selective GABAB receptor antagonist
Purity:>98%
CGP 55845 hydrochloride (HB0960)
Description:Potent, selective GABAB receptor antagonist
Purity:>98%
CGS 21680 hydrochloride (HB2097)
Description:Prototypic, selective A2A receptor agonist
Purity:>98%