Selective GABAB receptor antagonist (IC50 = 34 µM). Improves learning and neuromuscular function in a model of ischemia. Shows pro-epileptic actions. Blood-brain barrier permeable.
Solubility & Handling
Solubility overview
Soluble in water (100mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
CGP 35348, GABA B receptor antagonist, has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage.
Gillani Q et al (2014) Biomed Res Int 2014 : 295215