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CGP 35348

(HB0955)
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Technical documents: SDS CoA Datasheet
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Product overview

Name CGP 35348
Description Selective GABAB receptor antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (2) References (3) Frequently bought together
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CGP 35348 product vial image | Hello Bio
CGP 35348 product vial image | Hello Bio

CGP 35348 product vial image | Hello Bio

CGP 35348 product vial image | Hello Bio

Biological Data

Biological description Selective GABAB receptor antagonist (IC50 = 34 µM). Improves learning and neuromuscular function in a model of ischemia. Shows pro-epileptic actions. Blood-brain barrier permeable.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name (3-Aminopropyl)(diethoxymethyl)phosphinic acid
Molecular Weight 225.22
Chemical structure CGP 35348 [123690-79-9] Chemical Structure
Molecular Formula C8H20NO4P
CAS Number 123690-79-9
PubChem identifier 107699
SMILES NCCCP(C(OCC)OCC)(O)=O
InChiKey QIIVUOWTHWIXFO-UHFFFAOYSA-N

References for CGP 35348

References are publications that support the biological activity of the product

  • CGP 35348, GABA B receptor antagonist, has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage.

    Gillani Q et al (2014) Biomed Res Int 2014 : 295215
    Read more (PubMedID: 24804211)

  • Involvement of GABA(B) receptors in convulsant-induced epileptiform activity in rat neocortex in vitro.

    Sutor B et al (1998) Eur J Neurosci 10(11) : 3417-27.
    Read more (PubMedID: 9824455)

  • CGP 35348: a centrally active blocker of GABAB receptors.

    Olpe HR et al (1990) Eur J Pharmacol 187(1) : 27-38.
    Read more (PubMedID: 2176979)

3 Item(s)

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Grouped product items
Order: HB0955
Pack PriceQty
10mg
$149
50mg
$581
Selective GABAB receptor antagonist
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Standard: $35

Hazardous: $35

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