Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
UBP145 (HB4717)
Description:Selective antagonist for GluN2D subunit containing NMDA receptors
Purity:>97%
UBP 302 (HB0627)
Description:Potent, selective GluK1 subunit selective kainate receptor antagonist
Purity:>98%
UBP 310 (HB0628)
Description:Potent, selective GluK1 / GluK3 subunit selective kainate receptor antagonist
Purity:>98%
UBP709 (HB9204)
Description:NMDAR pan-PAM that potentiates all GluN2 subunits. Enhances LTD and decreases LTP.Â
Purity:>98%
UBP714 ammonium salt (HB8161)
Description:NMDAR PAM which potentiates GluN2A and GluN2B with minimal effects on 2C and 2D.
Purity:>98%
UCPH 101 (HB0630)
Description:UCPH-101 is a potent, selective, non-competitive EAAT1 inhibitor
Purity:>98%