DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 631-640 of 747

Set Descending Direction
  1. Stigmasterol (HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity:

    >95%

    Pack:
    5g
    Price:
    $242
    Qty:
  2. Pack:
    10mg
    Price:
    $235
    Qty:
    Pack:
    50mg
    Price:
    $887
    Qty:
  3. Streptochlorin (HB4096)

    Description:

    TNFα-induced NF-κB activation inhibitor.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $396
    Qty:
  4. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $138
    Qty:
  5. Pack:
    100mg
    Price:
    $91
    Qty:
  6. Pack:
    100mg
    Price:
    $45
    Qty:
  7. Swinholide A (HB4100)

    Description:

    Actin filament inhibitor. Disrupts actin cytoskeleton.

    Purity:

    >97%

    Pack:
    50μg
    Price:
    $398
    Qty:
  8. TAK 715 (HB0599)

    Description:

    Potent, p-38 MAP kinase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $209
    Qty:
    Pack:
    50mg
    Price:
    $825
    Qty:
  9. Pack:
    5mg
    Price:
    $130
    Qty:
    Pack:
    10mg
    Price:
    $248
    Qty:
  10. Tamoxifen (HB0601)

    Description:

    Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $58
    Qty:
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