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(S)-(-)-Sulpiride

(HB1836)
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Product overview

Name (S)-(-)-Sulpiride
Purity >99%
Description Selective D2-like receptor antagonist. Active enantiomer.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Selective D2-like receptor antagonist. Active enantiomer. (Ki values are 2.5 and 8 nM at D2, D3, >1000 nM at D4, D5 and D1 receptors respectively). Antipsychotic. Active in vivo.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
Molecular Weight 341.42
Chemical structure (S)-(-)-Sulpiride [23672-07-3] Chemical Structure
Molecular Formula C15H23N3O4S
CAS Number 23672-07-3
PubChem identifier 688272
SMILES NS(C1=CC(C(NC[C@]2([H])CCCN2CC)=O)=C(OC)C=C1)(=O)=O
InChiKey BGRJTUBHPOOWDU-NSHDSACASA-N

References for (S)-(-)-Sulpiride

References are publications that support the biological activity of the product

  • Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.

    Dong E et al (2008) Proc Natl Acad Sci U S A 105(36) : 13614-9.
    Read more (PubMedID: 18757738)

  • Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects.

    Strange PG (2001) Pharmacol Rev 53(1) : 119-33.
    Read more (PubMedID: 11171942)

  • Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.

    Sunahara RK et al (1991) Nature 350(6319) : 614-9.
    Read more (PubMedID: 1826762)

3 Item(s)

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Order: HB1836
Pack PriceQty
100mg
$91
Selective D2-like receptor antagonist. Active enantiomer.
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Hazardous: $35

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