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Biological Data
| Biological description | Cell permeable dimeric dilactone macrolide. Cytotoxic compound. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin). Depolymerizes actin filaments (F-actin). Antifungal. Apoptosis inducer. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription. |
Solubility & Handling
| Storage instructions | +4°C |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical structure | ![Swinholide A [95927-67-6] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Swinholide A [95927-67-6]") |
| InChiKey | RJVBVECTCMRNFG-VGHOFLFQSA-N |
Actin filament inhibitor. Disrupts actin cytoskeleton.
![Swinholide A [95927-67-6] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb4100.png "Swinholide A [95927-67-6]")
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