Swinholide A

(HB4100)

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Product overview

Name Swinholide A
Purity >97%
Description Actin filament inhibitor. Disrupts actin cytoskeleton.
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Biological Data

Biological description Cell permeable dimeric dilactone macrolide. Cytotoxic compound. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin). Depolymerizes actin filaments (F-actin). Antifungal. Apoptosis inducer. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >97%
Molecular Weight 1389.9
Chemical structure Swinholide A [95927-67-6] Chemical Structure
CAS Number 95927-67-6
InChiKey RJVBVECTCMRNFG-VGHOFLFQSA-N
Appearance Colorless oil