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STO-609 acetate

(HB0593)
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Technical documents: SDS CoA Datasheet
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Product overview

Name STO-609 acetate
Purity >97%
Customer comments

Cheap and quick delivery. Verified customer, Seoul National University

Description Selective, competitive CaM-KK inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (1) References (3) Frequently bought together
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STO-609 acetate product vial image | Hello Bio
STO-609 acetate product vial image | Hello Bio

STO-609 acetate product vial image | Hello Bio

STO-609 acetate product vial image | Hello Bio

Biological Data

Biological description Selective, competitive, cell permeable CaM-KK (Ki values are 80 and 15 ng/ml for CaM-KKα and CaM-KKβ respectively). Shows selectivity for CaM-KK without any significant effect on downstream CaM kinases (CaM-KI and -IV).

Solubility & Handling

Storage instructions Room temperature (desiccate)
Solubility overview Soluble in NaOH(aq) (45mM) or DMSO (10mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >97%
Chemical name 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate
Molecular Weight 374.35
Chemical structure STO-609 acetate [1173022-21-3] Chemical Structure
Molecular Formula C19H10N2O3.C2H4O2
CAS Number 1173022-21-3
PubChem identifier 16760660
SMILES CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
Source Synthetic
InChi InChI=1S/C19H10N2O3.C2H4O2/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18;1-2(3)4/h1-9H,(H,23,24);1H3,(H,3,4)
InChiKey WNRSTFUVBWNELX-UHFFFAOYSA-N
MDL number MFCD06411456
Appearance Yellow solid

References for STO-609 acetate

References are publications that support the biological activity of the product

  • Inhibition of Ca<sup>2+</sup>/calmodulin-dependent protein kinase kinase 2 stimulates osteoblast formation and inhibits osteoclast differentiation.

    Cary RL et al (2013) J Bone Miner Res 28(7) : 1599-610.
    Read more (PubMedID: 23408651)

  • Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).

    Monteiro P et al (2008) Drug Metab Dispos 36(12) : 2556-63.
    Read more (PubMedID: 18755850)

  • STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase.

    Tokumitsu H et al (2002) J Biol Chem 277(18) : 15813-8.
    Read more (PubMedID: 11867640)

3 Item(s)

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Order: HB0593
Pack PriceQty
10mg
$235
50mg
$887
Selective, competitive CaM-KK inhibitor
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Standard: $35

Hazardous: $35

Shipped on ice: $35

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