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DL-AP4

(HB0249)
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Technical documents: SDS CoA Datasheet
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Product overview

Name DL-AP4
Alternative names 2-amino-4-phosphonobutyrate; 2APB
Purity >98%
Customer comments

Great Price! We are using this (DL-AP4) to block transmission through the ON-pathway in retinal bipolar cells; it seems to work well, and the price is great! Verified customer, Washington State University

Description Broad spectrum glutamate antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (4) Reviews (1) References (3) Frequently bought together
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Images

DL-AP4 product vial image | Hello Bio
DL-AP4 product vial image | Hello Bio

DL-AP4 product vial image | Hello Bio

DL-AP4 product vial image | Hello Bio

Biological Data

Biological description Broad spectrum glutamate antagonist. Produces depolarizing responses in the cerebral cortex for a short time period after quisqualate application.

Solubility & Handling

Solubility overview Soluble in water (33mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >98%
Chemical name DL-2-Amino-4-phosphonobutyric acid
Molecular Weight 183.1
Chemical structure DL-AP4 [6323-99-5] Chemical Structure
Molecular Formula C4H10NO5P
CAS Number 6323-99-5
PubChem identifier 2207
SMILES C(CP(=O)(O)O)C(C(=O)O)N
Source Synthetic
InChi InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
InChiKey DDOQBQRIEWHWBT-UHFFFAOYSA-N
MDL number MFCD00013999
Appearance White solid

References for DL-AP4

References are publications that support the biological activity of the product

  • Anion transport blockers inhibit DL-2-amino-4-phosphonobutyrate responses induced by quisqualate in the rat cerebral cortex.

    Turner JP (1993) Br J Pharmacol 109(2) : 449-58.
    Read more (PubMedID: 7689393)

  • The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations.

    Evans RH et al (1982) Br J Pharmacol 75(1) : 65-75.
    Read more (PubMedID: 7042024)

  • Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog.

    Evans RH et al (1979) Br J Pharmacol 67(4) : 591-603.
    Read more (PubMedID: 316343)

3 Item(s)

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Order: HB0249
Pack PriceQty
50mg
$48
Broad spectrum glutamate antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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