L-type calcium channel blocker. Decreases eNOS expression in the aorta. Shows antiproliferative, antihypertensive, antioxidant, anti-inflammatory, vasoprotective and neuroprotective actions.
Solubility & Handling
Solubility overview
Soluble in water (10mM) and in DMSO (100mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Calcium channel blockades exhibit anti-inflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the N(G)-nitro-L-arginine methyl ester-induced hypertensive rat aorta
Toba H et al (2005) Hypertens Res 28(8) : 689-700.
Calcium channel blockades exhibit anti-inflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the N(G)-nitro-L-arginine methyl ester-induced hypertensive rat aorta
Toba H et al (2005) Hypertens Res 28(8) : 689-700.
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