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Anacardic acid

(HB1380)
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Product overview

Name Anacardic acid
Alternative names AA
Purity >97%
Description Non-competitive HAT inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description Non-competitive histone acetyltransferase (HAT) inhibitor. Inhibits p300/CBP and p300-associated factor HAT actions (IC50 values are 5 and 8.5 µM respectively). Also inhibits NF-κB, induces ER stress and autophagy. Shows anti-cancer and anti-inflammatory actions.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in DMSO (100mM) or ethanol (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >97%
Chemical name 2-Hydroxy-6-pentadecylbenzoic acid
Molecular Weight 348.52
Chemical structure Anacardic acid [16611-84-0] Chemical Structure
Molecular Formula C22H36O3
CAS Number 16611-84-0
PubChem identifier 167551
SMILES OC1=C(C(O)=O)C(CCCCCCCCCCCCCCC)=CC=C1
InChiKey ADFWQBGTDJIESE-UHFFFAOYSA-N

References for Anacardic acid

References are publications that support the biological activity of the product

  • Induction of the endoplasmic reticulum stress and autophagy in human lung carcinoma A549 cells by anacardic acid.

    Seong YA et al (2014) Cell Biochem Biophys 68(2) : 369-77.
    Read more (PubMedID: 23955513)

  • Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the i

    Sung B et al (2008) Blood 111(10) : 4880-91.
    Read more (PubMedID: 18349320)

  • Small molecule modulators of histone acetyltransferase p300.

    Balasubramanyam K et al (2003) J Biol Chem 278(21) : 19134-40.
    Read more (PubMedID: 12624111)

3 Item(s)

Grouped product items
Order: HB1380
Pack PriceQty
5mg
$74
10mg
$111
Non-competitive HAT inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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