Non-competitive histone acetyltransferase (HAT) inhibitor. Inhibits p300/CBP and p300-associated factor HAT actions (IC50 values are 5 and 8.5 µM respectively). Also inhibits NF-κB, induces ER stress and autophagy. Shows anti-cancer and anti-inflammatory actions.
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (50mM)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the i