Non-competitive histone acetyltransferase (HAT) inhibitor. Inhibits p300/CBP and p300-associated factor HAT actions (IC50 values are 5 and 8.5 µM respectively). Also inhibits NF-κB, induces ER stress and autophagy. Shows anti-cancer and anti-inflammatory actions.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in DMSO (100mM) or ethanol (50mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the i