DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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UBP 302 (HB0627)
Description:Potent, selective GluK1 subunit selective kainate receptor antagonist
Purity:>98%
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UBP 310 (HB0628)
Description:Potent, selective GluK1 / GluK3 subunit selective kainate receptor antagonist
Purity:>98%
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UCPH 101 (HB0630)
Description:UCPH-101 is a potent, selective, non-competitive EAAT1 inhibitor
Purity:>98%
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Urapidil hydrochloride (HB1693)
Description:Selective 5-HT1A agonist. α1-adrenoceptor antagonist
Purity:>99%
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Valproic acid sodium salt (HB0867)
Description:Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells.
