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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Pyripyropene A (HB4044)
Description:Highly specific acyl-coenzyme A cholesterol acetyltransferase 2 inhibitor
Purity:>95%
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QNZ 46 (HB0541)
Description:GluN2C/D selective, non-competitive NMDA receptor antagonist
Purity:>98%
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Quetiapine hemifumarate (HB1803)
Description:5-HT2 and D2 antagonist. Atypical antipsychotic.
Purity:>99%
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Q-VD-OPh (HB4048)
Description:Cell permeable, irreversible and non-toxic pan-caspase inhibitor
Purity:>95%
