DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 291-300 of 1078

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  1. 1  Review
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    Description:

    Blue fluorescent DNA stain. Nuclear counterstain. 1mg/mL staining solution in water. Solid also available in 10mg and 50mg packs.

    Pack:
    1mL
    Price:
    Qty:
    Pack:
    5mL
    Price:
    $516
    Qty:
  2. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $414
    Qty:
  3. DAPT (HB3345)

    1  Review
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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    25mg
    Price:
    $418
    Qty:
    Pack:
    50mg
    Price:
    $703
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
    Qty:
  4. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $147
    Qty:
    Pack:
    10mg
    Price:
    $185
    Qty:
    Pack:
    50mg
    Price:
    $773
    Qty:
  5. H2DCFDA (HB8322)

    Description:

    Fluorescent dye for ROS and oxidative stress detection. Used to measure redox state of a cell.

    Pack:
    100mg
    Price:
    $70
    Qty:
  6. Pack:
    50mg
    Price:
    $835
    Qty:
    Pack:
    1mg
    Price:
    $34
    Qty:
    Pack:
    5mg
    Price:
    $131
    Qty:
    Pack:
    10mg
    Price:
    $215
    Qty:
  7. Description:

    Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $118
    Qty:
    Pack:
    1mg
    Price:
    $173
    Qty:
    Pack:
    5mg
    Price:
    $777
    Qty:
  8. Description:

    Cholesterol biosynthesis inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $441
    Qty:
  9. Description:

    TGF-β signaling inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $502
    Qty:
  10. Description:

    Specific DNA polymerase α inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $250
    Qty:
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