DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Malformin C (HB3966)
Description:Antibiotic. Potent G2 checkpoint cell cycle arrest inhibitor
Purity:>95%
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Anti-MAP2 antibody ValidAbTM (HB9587)
Description:Antibody to MAP2 - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat -
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MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 (HB9059)
Description:SARS-CoV Mpro FRET substrate suitable for measuring Mpro & SARS-Cov Mpro protease activity
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MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
