DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%
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(R,R)-Hymeglusin (HB3701)
Description:Specific and irreversible HMG-CoA synthase inhibitor
Purity:>95%
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10Z-Hymenialdisine (HB1264)
Description:Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.
Purity:>97%
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Hyperforin dicyclohexylammonium (HB3933)
Description:Selective TRPC6 channel activator and neurotransmitter re-uptake inhibitor
Purity:>97%
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Hypericin (HB3934)
Description:Photosensitive compound. Shows anticancer, antiviral and antidepressant action.
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Anti-IBA1 antibody ValidAbTM (HB7847)
Description:Antibody to IBA1 - calcium binding protein widely used as a marker for microglial cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat -
