G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Janelia Fluor® 525, SE (HB8455)
Description:Yellow dye for coupling to NHS groups. Suitable for super resolution microscopy (e.g. dSTORM), confocal microscopy and live cell imaging.
Janelia Fluor® 549, Azide (HB7988)
Description:Yellow dye supplied as an azide for click chemistry. Suitable for dSTORM, STED, confocal microscopy, live cell imaging and flow cytometry.
Janelia Fluor® 549, Tetrazine (HB7228)
Description:Yellow dye supplied with a tetrazine reactive handle for copper-free click chemistry. Suitable for dSTORM, STED, confocal microscopy and live cell imaging.
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%
Janelia Fluor® 549, free acid (HB8745)
Description:Yellow dye supplied as a free acid. Suitable for dSTORM, STED, confocal microscopy, live cell imaging and flow cytometry.
Janelia Fluor® 549, SE (HB7336)
Description:Yellow dye for coupling to NHS groups. Suitable for dSTORM, STED, confocal microscopy, live cell imaging and flow cytometry.
LUF7487 (HB9585)
Description:Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A2AR.
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.