HMG-CoA synthase

Matrix metalloproteinase-1 (MMP-1) inhibitor

CCR5 receptor antagonist

Endogenous inhibitory neurotransmitter

Broad spectrum glutamate antagonist

GLI1 antagonist. Hedgehog signaling inhibitor.

GLI antagonist. Also Hedgehog (Hh) signaling inhibitor.

Cx43 hemichannel blocker

Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.

Potent, competitive dopamine uptake inhibitor

Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.